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For those that have been keeping pace with my posts on the role of glycation in the processes that constitute the “hallmarks” of aging, you will note that there are recurring elements we continue to discuss (even if from a somewhat different angle). By now I hope readers can appreciate that the given altered mechanics
by Nicholas Pokoluk Human cellular functions and lifecycles are very rigorously controlled. This control is carried out by intra and extracellular signals that effect proliferation, senescence and apoptosis. There are many nutrient signaling pathways including AKT, mTOR, FOXO and Insulin/Insulin-like Growth Factor 1 (IGF-1) pathways that are all interconnected at some point. The I/IGF-1 glucose
What are Epigenics and How Does It Play a Roll in Aging? Epigenetics is a term used for gene expression modifications caused by heritable, but potentially reversible, changes in DNA linked processes. These processes include DNA methylations, modifications of histones and chromatin structural changes. DNA methylation modifies a DNA strand after replication. It is
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